![]() ![]() ![]() The 12 genes with the highest level of regional enriched expression within the mouse brain and the regional distribution category. Transcriptomic data from the different regions facilitates classification of the regional expression variation within mouse brain. The regional organization of brain anatomy separates the brain into regions, sub regions, nuclei and layers of specialized cells, enabling the specific function of each individual region. Many of the mouse proteins have extensive homology with the human counterpart and this forms the basis of for using the mouse brain as a model for the corresponding human brain to explore the expression and distribution of proteins in the various regions and cells of the brain. The driving force in evolution is genetic variability passed on from one generation to the other. These evolutionary processes mainly involve size expansion, not affecting the basic architecture of the brain and gene-expression in the various cell types that populate the brain. Within mammalian evolution, the brain has undergone changes that resulted in increased capacities to process information and perform higher cognitive functions in primates and humans. ![]()
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